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Mary Jean Brown, ScD, RN and Patrick J. Meehan, MD, MPH

The authors are with the National Center for Environmental Health/Agency for Toxic Substances and Disease Registry, Centers for Disease Control and Prevention, Atlanta, Ga.

Correspondence: Requests for reprints should be sent to Mary Jean Brown, ScD, RN, Lead Poisoning Prevention Branch, Mail Stop F-30, 4770 Buford Hwy NE, Atlanta, GA 30341 (e-mail: mjb5{at}cdc.gov).

The thoughtful commentary provided by Bernard¹ is a welcome addition to deliberations about whether the Centers for Disease Control and Prevention (CDC) should respond to recent reports of adverse effects of blood lead levels (BLLs) lower than 10 µg/dL in children by lowering the BLL at which individual intervention is recommended.^2,3 The CDC’s Advisory Committee on Childhood Lead Poisoning Prevention is reviewing the scientific evidence of the health effects of BLLs lower than 10 µg/dL in children. A finding of adverse effects across a large number of studies will raise important questions about what changes, if any, the CDC should make in its recommendations for medical and environmental management of individual cases. Several suggested changes, including Bernard’s suggestion that very young children with BLLs above the national average for young children be tested more frequently, deserve further consideration.

Bernard also advocates widespread education about the dangers of lead, the use of blood lead surveillance and other data (such as housing data) to identify populations at risk, and improved screening of children enrolled in Medicaid. We concur with these recommendations and have asked state and local programs funded by the CDC to work aggressively in these areas. We also agree that control or elimination of lead hazards is essential in "repeat offender" housing where children with elevated BLLs have repeatedly been identified.

Also relevant to these considerations is the lack of effective interventions to lower elevated BLLs.^4,5 Taken together with the recent reports of health effects of BLLs lower than 10 µg/dL, these studies suggest that elimination of childhood lead exposure requires the implementation of creative strategies for primary prevention. However, shifting our focus to primary prevention does not require changing the intervention level or preclude using this level as one tool for identifying populations of children at highest risk. In fact, it is extremely important that we continue to focus our efforts on those populations. Moreover, we believe that primary prevention efforts, including effective partnerships with housing and other agencies to direct scarce abatement and prevention resources to high-risk neighborhoods, should be our highest priority. Emphasizing primary prevention is the only way we can achieve the nation’s 2010 health objective of eliminating childhood lead poisoning as a public health problem.⁶

References

1. Bernard SM. Should the Centers for Disease Control and Prevention childhood lead poisoning intervention level be lowered? Am J Public Health. 2003;93:1253–1260.[Abstract/Free Full Text]

2. Canfield RL, Henderson CR Jr, Cory-Slechta DA, Cox C, Jusko TA, Lanphear BP. Intellectual impairment in children with blood lead concentrations below 10 µg per deciliter. N Engl J Med. 2003;348:1517–1526.[Abstract/Free Full Text]

3. Bellinger DC, Needleman HL. Intellectual impairment and blood lead levels. N Engl J Med. 2003;349:502.[Free Full Text]

4. Lanphear BP, Howard C, Eberly S, et al. Primary prevention of childhood lead exposure: a randomized trial of dust control. Pediatrics. 1999;103:772–777.[Abstract/Free Full Text]

5. Rogan WJ, Dietrich KN, Ware JH, et al. The effect of chelation therapy with succimer on neuropsychological development in children exposed to lead. N Engl J Med. 2001;344:1421–1426.[Abstract/Free Full Text]

6. Healthy People 2010. 2nd ed. Washington, DC: US Department of Health and Human Services; 2000.

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This Article Extract Full Text (PDF) Submit a response Purchase Article View Shopping Cart Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Brown, M. J. Articles by Meehan, P. J. Search for Related Content PubMed PubMed Citation Articles by Brown, M. J. Articles by Meehan, P. J. Related Collections Community Health Epidemiology Minority Children Lead Health Policy Government