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LETTER |
The authors are with the Department of Medicine, Cambridge Health Alliance, Cambridge, MA, and the Harvard Medical School, Cambridge.
Correspondence: Requests for reprints should be sent to Sarah L. Cutrona, Department of Medicine, Cambridge Hospital 1493 Cambridge St, Cambridge, MA 02139 (slcutrona@gmail.com).
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We appreciate the comments made by Vincent et al. They raise several important points about the disadvantages of free drug sample use.
Free samples tend to be newer, more costly medications.1 By influencing prescribing, samples increase pharmaceutical costs for patients.2 For indigent patients who are given prescriptions to use after the sample is exhausted, these high costs can be prohibitive, which might lead to nonadherence. Patients relying exclusively on free samples instead of using affordable generic options or patient assistance programs encounter different challenges. These patients face an inconsistent free-sample supply and difficulty returning to a providers office in time
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