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AJPH First Look, published online ahead of print Jan 31, 2006
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March 2006, Vol 96, No. 3 | American Journal of Public Health 398
© 2006 American Public Health Association
DOI: 10.2105/AJPH.2005.079731

LETTER

USING ADJUSTED RELATIVE RISKS TO CALCULATE ATTRIBUTABLE FRACTIONS

Katherine M. Flegal, PhD, David F. Williamson, PhD and Barry I. Graubard, PhD

Katherine M. Flegal is with the National Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Md. David F. Williamson is with the Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Ga. Barry I. Graubard is with the National Cancer Institute, Bethesda, Md.

Correspondence: Requests for reprints should be sent to Katherine M. Flegal, PhD, National Center for Health Statistics, 3311 Toledo Rd, Room 4311, Hyattsville MD 20782 (e-mail: kmf2@cdc.gov).

Because this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

Leveille et al.1 estimated population attributable fraction (PAF) values for arthritis attributable to obesity by using multivariate-adjusted relative risks and the body mass index distribution in the US population aged 40 through 74 years. It is important to adjust relative risk estimates for confounding factors such as age and gender that are associated with both arthritis and obesity. However, when relative risks are adjusted for confounding factors, it is also necessary to use properly adjusted estimators of attributable fraction to avoid bias.

The PAF formula cited by Leveille et al. is appropriate only for use with relative risks that are . . . [Full Text]






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