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Richard B. Warnecke, PhD, April Oh, MPH, Nancy Breen, PhD, Sarah Gehlert, PhD, Electra Paskett, PhD, Katherine L. Tucker, PhD, Nicole Lurie, MD, MSPH, Timothy Rebbeck, PhD, James Goodwin, MD, John Flack, MD, MPH, Shobha Srinivasan, PhD, Jon Kerner, PhD, Suzanne Heurtin-Roberts, PhD, MSW, Ronald Abeles, PhD, Frederick L. Tyson, PhD, Georgeanne Patmios, MA and Robert A. Hiatt, MD, PhD

Richard B. Warnecke and April Oh are with the Center for Population Health and Health Disparities (CPHHD), University of Illinois, Chicago. Nancy Breen, Shobha Srinivasan, and Jon Kerner are with the National Cancer Institute, National Institutes of Health, Bethesda, MD. Ronald Abeles is with the Office of Behavioral and Social Science Research, National Institutes of Health, Bethesda. Frederick L. Tyson is with the National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, and Georgeanne Patmios is with the National Institute on Aging, National Institutes of Health, Bethesda. Sarah Gehlert is with the Center for Interdisciplinary Health Disparities, University of Chicago, Chicago. Electra Paskett is with the CPHHD, Ohio State University, Columbus, and University of Michigan, Ann Arbor. Katherine L. Tucker is with the CPHHD, Tufts University and Northeastern University, Boston, MA. Nicole Lurie is with the CPHHD, RAND Corporation, Santa Monica, CA, Washington, DC, and Pittsburgh, PA. Timothy Rebbeck is with the CPHHD, University of Pennsylvania, Philadelphia. James Goodwin is with the CPHHD, University of Texas Medical Branch, Galveston. John Flack is with the Center for Urban and African American Health, Wayne State University, Detroit, MI. At the time of the study, Suzanne Heurtin-Roberts was with the Behavioral Research Program, National Cancer Institute, National Institutes of Health, Bethesda. Robert A. Hiatt is with the University of California, San Francisco.

Correspondence: Requests for reprints should be sent to Richard B. Warnecke, Program in Cancer Control and Population Science, University of Illinois Cancer Center, 1747 W Roosevelt Rd, Ste 558, MC 275, Chicago, IL 60608-1264 (e-mail: warnecke{at}uic.edu).

Addressing health disparities has been a national challenge for decades. The National Institutes of Health–sponsored Centers for Population Health and Health Disparities are the first federal initiative to support transdisciplinary multilevel research on the determinants of health disparities. Their novel research approach combines population, clinical, and basic science to elucidate the complex determinants of health disparities. The centers are partnering with community-based, public, and quasi-public organizations to disseminate scientific findings and guide clinical practice in communities. In turn, communities and public health agents are shaping the research. The relationships forged through these complex collaborations increase the likelihood that the centers’ scientific findings will be relevant to communities and contribute to reductions in health disparities.