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This Article Full Text Full Text (PDF) All Versions of this Article: AJPH.2005.078873v1 97/3/450    most recent Submit a response View Shopping Cart Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Similar articles in this journal Similar articles in ISI Web of Science Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via ISI Web of Science (1) Citing Articles via Google Scholar Google Scholar Articles by Kivimäki, M. Articles by Raitakari, O. T. Search for Related Content PubMed PubMed Citation Articles by Kivimäki, M. Articles by Raitakari, O. T. Related Collections Occupational Health Socioeconomic Factors Men's Health Cardiovascular Disease

Mika Kivimäki, PhD, Mirka Hintsanen, MSci, Liisa Keltikangas-Järvinen, PhD, Marko Elovainio, PhD, Laura Pulkki-Råback, PhD, Jussi Vahtera, MD, Jorma S.A. Viikari, MD and Olli T. Raitakari, MD

Mika Kivimäki is with the Department of Epidemiology and Public Health, University College London, London, England. Mirka Hintsanen, Liisa Keltikangas-Järvinen, and Laura Pulkki-Råback are with the Department of Psychology, University of Helsinki, Helsinki, Finland. Mika Kivimäki and Jussi Vahtera are with the Finnish Institute of Occupational Health, Helsinki. Marko Elovainio is with the National Research and Development Centre for Welfare and Health, Helsinki. Jorma S.A. Viikari is with the Department of Medicine and Olli T. Raitakari is with the Department of Clinical Physiology, University of Turku, Turku, Finland.

Correspondence: Requests for reprints should be sent to Mika Kivimäki, PhD, University College London, Department of epidemiology and public health, 1-19 Torrington Pl, London WC1E 6BT, UK (e-mail: m.kivimaki{at}ucl.ac.uk).

We examined whether preemployment influences confounded the association between job strain and atherosclerosis. We assessed biological, familial, and socioeconomic risk factors of coronary heart disease at 12 to 18 years of age and job strain and carotid artery intima-media thickness at 33 to 39 years of age for a cohort of 358 men.

Adolescent risk factors predicted adult intima-media thickness but had little effect on the dose–response relation between greater job strain and greater intima-media thickness. Pre-employment influences did not confound the association between job strain and atherosclerosis.

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