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AJPH First Look, published online ahead of print Jun 28, 2005
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95/8/1375    most recent
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August 2005, Vol 95, No. 8 | American Journal of Public Health 1375-1381
© 2005 American Public Health Association
DOI: 10.2105/AJPH.2004.048967


RESEARCH AND PRACTICE

Socioeconomic Risk Factors for Asthma in Chilean Young Adults

Camila Corvalán, MD, MPH, Hugo Amigo, DMD, DrPH, MPH, Patricia Bustos, MD and Roberto J. Rona, MD, FFPH, PhD

At the time of this study, Camila Corvalán was with the Department of Nutrition, School of Medicine, University of Chile, Santiago. Hugo Amigo and Patricia Bustos are with the Department of Nutrition, School of Medicine, University of Chile. Roberto Rona is with the Department of Public Health Sciences, King’s College, London, England.

Correspondence: Requests for reprints should be sent to Roberto J. Rona, Department of Public Health Sciences, King’s College London, 5th Floor, Capital House, 42 Weston St SE1 3QD, UK (e-mail: roberto.rona{at}kcl.ac.uk).

Objectives. We studied the association between socioeconomic status (SES) and asthma symptoms, severity of asthma, atopy, and bronchial hyperresponsiveness (BHR) to methacholine.

Methods. We studied 1232 men and women born between 1974 and 1978 in a semirural area of Chile. We assessed asthma symptoms with a standardized questionnaire, atopy with a skin-prick test to 8 allergens, and BHR to methacholine with the tidal breathing method. SES was derived from several indicators: education, occupation, completion of a welfare form, belongings, housing, number of siblings, and overcrowding.

Results. Those with fewer belongings had more asthma symptoms. Those who had higher education and those who owned cars had fewer asthma symptoms and BHR. Overcrowding was negatively related to atopy, atopy with asthma symptoms, and BHR. Higher education and noncompletion of a welfare form were risk factors for atopy.

Conclusion. The strength and direction of the association between asthma and SES depended on what definition of asthma was analyzed. Asthma symptoms were more common among poor people. There was some support for the hygiene hypothesis, as overcrowding was associated with less wheezing with atopy, less atopy, and less BHR.




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