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Claudia Langenberg, MD, Martin J. Shipley, MSc, G. David Batty, PhD and Michael G. Marmot, FRCP

Claudia Langenberg, Martin J. Shipley, and Michael G. Marmot are with the Department of Epidemiology and Public Health, University College London Medical School, London, England. G. David Batty is with the Department of Psychology, University of Edinburgh, Scotland, and Medical Research Council Social and Public Health Sciences Unit, University of Glasgow, Scotland.

Correspondence: Requests for reprints should be sent to Claudia Langenberg, MD, Department of Epidemiology and Public Health, University College London Medical School, 1–19 Torrington Pl, London, WC1E 6BT United Kingdom (e-mail: c.langenberg{at}ucl.ac.uk).

In the Whitehall Study, which followed 17139 male civil servants over 33 years, the association between tall stature and coronary heart disease (CHD) mortality differed between employment grades. In men without CHD at study entry, the hazard ratio per 15-cm increase in height was 0.77 (95% confidence interval [CI]=0.69, 0.85; P<0.001) for the highest grades, but 0.84 (95% CI=0.69, 1.03; P=.10) for middle and 0.95 (95% CI = 0.75, 1.20; P = .65) for low grades, suggesting that childhood and adult social conditions may interact in their influence on coronary risk.

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