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June 2004, Vol 94, No. 6 | American Journal of Public Health 958-959
© 2004 American Public Health Association

RESEARCH AND PRACTICE

Impact of PCV7 on Invasive Pneumococcal Disease Among Children Younger Than 5 Years: A Population-Based Study

Revathi R. Ramani, MD, MPH, William N. Hall, MD, MPH, Matthew Boulton, MD, MPH, David R. Johnson, MD, MPH and Bao-Ping Zhu, MD, MS

At the time of the study, all the authors were with the Michigan Department of Community Health, Lansing, Mich. Revathi R. Ramani and Matthew Boulton also were with the University of Michigan Preventive Medicine Residency Program, Ann Arbor.

Correspondence: Requests for reprints should be sent to William N. Hall, Bureau of Epidemiology, Mich Dept of Community Health, 3423 N Martin Luther King Blvd, Lansing, MI 48909 (e-mail: hallw{at}michigan.gov).

We examined the impact of the heptavalent pneumococcal conjugate vaccine (PCV7) on hospital discharge rates for invasive pneumococcal disease among Michigan children younger than 5 years old. After the introduction of PCV7, the hospital discharge rate for children younger than 1 years old was significantly lower than before introduction. We correlated the decreased rates with the introduction and rapid uptake of PCV7. Lack of change in the hospital discharge rates for other age groups likely represents a slower uptake of PCV7 compared with that for children aged younger than 1 year.




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