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William A. Vega, PhD, William M. Sribney, MS and Ijeoma Achara-Abrahams, PhD

William A. Vega is with the Behavioral Research and Training Institute, University Behavioral Health Care, University of Medicine and Dentistry—New Jersey, and the Department of Psychiatry, Robert Wood Johnson Medical School, Piscataway, NJ. William M. Sribney is with the Department of Genetics, Rutgers University, Piscataway. Ijeoma Achara-Abrahams is with the School of Public Health, Yale University, New Haven, Conn.

Correspondence: Requests for reprints should be sent to William A. Vega, PhD, Behavioral Research and Training Institute, University Behavioral Health Care, University of Medicine and Dentistry—New Jersey, 151 Centennial Ave, Piscataway, NJ 08854 (e-mail: vegawa{at}umdnj.edu).

We examined co-occurrence of (comorbid) alcohol, drug, and non–substance use psychiatric disorders in a population sample of Mexican-origin adults from rural and urban areas of central California.

Co-occurring lifetime rates of alcohol or other drug disorders with non–substance use psychiatric disorders, or both, were 8.3% for men and 5.5% for women and were 12.3% for the US born and 3.5% for immigrants.

Alcohol abuse or dependence with co-occurring psychiatric disorders is a primary disorder among Mexican-origin adult males (7.5% lifetime prevalence). US-born men and women are almost equally likely to have co-occuring disorders involving substances. Cobormidity is expected to increase in the Mexican-origin population owing to acculturation effects of both sexes.

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