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Harrell W. Chesson, PhD, Steven D. Pinkerton, PhD, Richard Voigt, MA and George W. Counts, MD

Harrell W. Chesson and Richard Voigt are with the Division of STD Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, Ga. Steven D. Pinkerton is with the Center for AIDS Intervention Research, Department of Psychiatry and Behavioral Medicine, Medical College of Wisconsin, Milwaukee. When this study was conducted, George W. Counts was with the Division of STD Prevention, CDC.

Correspondence: Requests for reprints should be sent to Harrell W. Chesson, PhD, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mail Stop E-80, Atlanta, GA 30324 (e-mail: hbc7{at}cdc.gov).

Objectives. We estimated the number and cost of syphilis-attributable HIV cases among African Americans.

Methods. A mathematical model of HIV transmission was used to estimate the number of partnerships consisting of HIV-discordant African Americans in which infectious syphilis was present and the number of new HIV cases attributable to syphilis in these partnerships.

Results. In 2000, an estimated 545 new cases of HIV infection among African Americans could be attributed to the facilitative effects of infectious syphilis, at a cost of about $113 million.

Conclusions. Syphilis prevention could reduce HIV incidence rates and the disproportionate burden of HIV/AIDS on the African American community, resulting in substantial reductions in future HIV/AIDS medical costs.

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				N. M. Zetola, J. Engelman, T. P. Jensen, and J. D. Klausner Syphilis in the United States: An Update for Clinicians With an Emphasis on HIV Coinfection Mayo Clin. Proc., September 1, 2007; 82(9): 1091 - 1102. [Abstract] [Full Text] [PDF]