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American Journal of Public Health, Vol 91, Issue 7 1117-1120, Copyright © 2001 by American Public Health Association

JOURNAL ARTICLE

Circumstances at HIV diagnosis and progression of disease in older HIV-infected Americans

DS Zingmond, NS Wenger, S Crystal, GF Joyce, H Liu, U Sambamoorthi, LA Lillard, AA Leibowitz, MF Shapiro and SA Bozzette
Division of General Internal Medicine and Health Services Research, UCLA Department of Medicine, 911 Broxton Plaza, Los Angeles, CA 90095-1736, USA. dzingmond@mednet.ucla.edu

OBJECTIVES: This study identified age-related differences in diagnosis and progression of HIV by analyzing a nationally representative sample of HIV-infected adults under care in the United States. METHODS: We compared older (> or = 50 years) and younger participants stratified by race/ethnicity. Regression models controlled for demographic, therapeutic, and clinical factors. RESULTS: Older non-Whites more often had HIV diagnosed when they were ill. Older and younger patients were clinically similar. At baseline, however, older non-Whites had fewer symptoms and were less likely to have AIDS, whereas at follow-up they had a trend toward lower survival. CONCLUSIONS: Later HIV diagnosis in non-Whites merits public health attention; clinical progression in this group requires further study.


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