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American Journal of Public Health, Vol 91, Issue 7 1089-1093, Copyright © 2001 by American Public Health Association

JOURNAL ARTICLE

Effects of alcohol-related disease on hip fracture and mortality: a retrospective cohort study of hospitalized Medicare beneficiaries

Z Yuan, N Dawson, GS Cooper, D Einstadter, R Cebul and AA Rimm
Department of Epidemiology and Biostatistics, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA. yuan@hal.cwru.edu

OBJECTIVES: This study investigated the effect of alcohol-related disease on hip fracture and mortality. METHODS: A retrospective cohort design was used. The study cohort consisted of hospitalized Medicare beneficiaries with alcohol-related disease (n = 150,119) and randomly matched controls without alcohol-related disease (n = 726,218) identified through the 1988-1989 inpatient claims file. Incidence rates of hip fracture and mortality were examined. RESULTS: During the study period, 20,620 patients developed hip fracture, with 6973 cases among patients with alcohol-related disease and 13,647 cases among patients without alcohol-related disease. After adjustment for potential confounders, patients with alcohol-related disease had a 2.6-fold increased risk of hip fracture relative to patients without alcohol-related disease (95% confidence interval = 2.5, 2.6). Patients with alcohol-related disease had a higher risk of mortality at 1 year after hip fracture. CONCLUSIONS: Alcohol-related disease increases the risk of hip fracture significantly and reduces long-term survival. The present results suggest that patients hospitalized for alcohol-related disease should be targeted for hip fracture prevention programs.


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L. HOWARD, G. KIRKWOOD, and M. LEESE
Risk of hip fracture in patients with a history of schizophrenia
The British Journal of Psychiatry, February 1, 2007; 190(2): 129 - 134.
[Abstract] [Full Text] [PDF]


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