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American Journal of Public Health, Vol 91, Issue 3 412-417, Copyright © 2001 by American Public Health Association

JOURNAL ARTICLE

Evaluating OSHA's ethylene oxide standard: exposure determinants in Massachusetts hospitals

AD LaMontagne and KT Kelsey
Center for Community-Based Research, Department of Adult Oncology, Dana-Farber Cancer Institute, Boston, Mass., USA. anthony.lamontagne@med.monash.edu.au

OBJECTIVES: This study sought to identify determinants of workplace exposures to ethylene oxide to assess the effect of the Occupational Safety and Health Administration's (OSHA's) 1984 ethylene oxide standard. METHODS: An in-depth survey of all hospitals in Massachusetts that used ethylene oxide from 1990 through 1992 (96% participation, N = 90) was conducted. Three types of exposure events were modeled with logistic regression: exceeding the 8-hour action level, exceeding the 15-minute excursion limit, and worker exposures during unmeasured accidental releases. Covariates were drawn from data representing an ecologic framework including direct and indirect potential exposure determinants. RESULTS: After adjustment for frequencies of ethylene oxide use and exposure monitoring, a significant inverse relation was observed between exceeding the action level and the use of combined sterilizer-aerators, an engineering control technology developed after the passage of the OSHA standard. Conversely, the use of positive-pressure sterilizers that employ ethylene oxide gas mixtures was strongly related to both exceeding the excursion limit and the occurrence of accidental releases. CONCLUSIONS: These findings provide evidence of a positive effect of OSHA's ethylene oxide standard and specific targets for future prevention and control efforts.


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A. D. LaMontagne, J. M. Oakes, and R. N. Lopez Turley
Long-Term Ethylene Oxide Exposure Trends in US Hospitals: Relationship With OSHA Regulatory and Enforcement Actions
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[Abstract] [Full Text] [PDF]


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