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Blood pressure level and incidence of myocardial infarction among patients treated for hypertension.

R C Kaplan, B M Psaty, S R Heckbert, N L Smith and R N Lemaitre

Cardiovascular Health Research Unit, University of Washington, Seattle, USA. rkaplan@u.washington.edu

OBJECTIVES: This study examined the relationship between achieved blood pressure and risk of myocardial infarction among patients treated for hypertension. METHODS: Blood pressure and other cardiovascular risk factors were assessed among 718 myocardial infarction case patients and 2136 matched controls. RESULTS: Blood pressure level was directly related to risk of myocardial infarction. Patients with treated hypertension who had mild elevations in blood pressure accounted for a larger share of the excess myocardial infarction incidence than those who had higher blood pressure readings. CONCLUSIONS: Achieving normotensive levels in treated hypertensive patients with uncontrolled blood pressure might prevent more than 15% of myocardial infarctions in the treated hypertensive population.

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