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Department of Health and Social Behavior, Harvard School of Public Health, Boston, MA 02115, USA.
OBJECTIVES: This study examined how patient acceptability influences the effectiveness of directly observed therapy for tuberculosis. METHODS: Decision and sensitivity analyses were used in assessing influences. RESULTS: If mandatory directly observed therapy discourages 6% of initial tuberculosis patients (range: 4% to 10%) from seeking care, then such therapy will be less effective than self-administered therapy. Directly observed therapy is more effective than repeated self-administered therapy for patients failing to complete initial treatment unless 32% (range: 27% to 38%) of patients avoid seeking care. CONCLUSIONS: Patient acceptability must be taken into consideration before selecting public health strategies.
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R. Coker, M. Thomas, K. Lock, and R. Martin Detention and the Evolving Threat of Tuberculosis: Evidence, Ethics, and Law J. Law Med. Ethics, December 1, 2007; 35(4): 609 - 615. [PDF] |
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