| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Department of Family and Preventive Medicine, University of California, San Diego.
OBJECTIVES. Previous studies have reported positive associations of age at menopause with bone density and inverse associations of age at menarche with bone density. This study examined the relationships of early age at menopause and number of reproductive years (defined as age at menopause minus age at menarche) with bone density in postmenopausal women. METHODS. The subjects were 555 women aged 60 to 89 years who had had either natural menopause (n = 391) or hysterectomy with bilateral oophorectomy (n = 164). Bone density was measured at the ultradistal wrist, midshaft radius, lumbar spine, and hip. RESULTS. Women who had had early menopause and those with the fewest reproductive years had significantly lower bone density at all sites. After adjustment for covariates, both age at menopause and number of reproductive years had significant positive associations with bone density at every site, and total number of reproductive years explained more of the variance in bone mineral density than did either age at menarche or age at menopause. CONCLUSIONS. Elderly women reporting early menopause or fewer reproductive years have more osteoporosis. The number of reproductive years may be more helpful than age at menopause in identifying women at increased risk of osteoporosis.
This article has been cited by other articles:
|
|
 |
|
  J. J. DE CARO, C. DOMINGUEZ, and S. L. SHERMAN Reproductive Health of Adolescent Girls Who Carry the FMR1 Premutation: Expected Phenotype Based on Current Knowledge of Fragile X-Associated Primary Ovarian Insufficiency Ann. N.Y. Acad. Sci., June 1, 2008; 1135(1): 99 - 111. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Rohr, E.G. Allen, K. Charen, J. Giles, W. He, C. Dominguez, and S.L. Sherman Anti-Mullerian hormone indicates early ovarian decline in fragile X mental retardation (FMR1) premutation carriers: a preliminary study Hum. Reprod., May 1, 2008; 23(5): 1220 - 1225. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Varenna, L. Binelli, S. Casari, F. Zucchi, and L. Sinigaglia Effects of dietary calcium intake on body weight and prevalence of osteoporosis in early postmenopausal women Am. J. Clinical Nutrition, September 1, 2007; 86(3): 639 - 644. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. E. Cejtin, A. Kalinowski, P. Bacchetti, R. N. Taylor, D. H. Watts, S. Kim, L. S. Massad, S. Preston-Martin, K. Anastos, M. Moxley, et al. Effects of Human Immunodeficiency Virus on Protracted Amenorrhea and Ovarian Dysfunction Obstet. Gynecol., December 1, 2006; 108(6): 1423 - 1431. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. B. Nichols, A. Trentham-Dietz, J. M. Hampton, L. Titus-Ernstoff, K. M. Egan, W. C. Willett, and P. A. Newcomb From Menarche to Menopause: Trends among US Women Born from 1912 to 1969 Am. J. Epidemiol., November 15, 2006; 164(10): 1003 - 1011. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. E. Hatch, R. Troisi, L. A. Wise, M. Hyer, J. R. Palmer, L. Titus-Ernstoff, W. Strohsnitter, R. Kaufman, E. Adam, K. L. Noller, et al. Age at Natural Menopause in Women Exposed to Diethylstilbestrol in Utero Am. J. Epidemiol., October 1, 2006; 164(7): 682 - 688. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. S. Kok, K. M. van Asselt, Y. T. van der Schouw, P. H.M. Peeters, and C. Wijmenga Genetic studies to identify genes underlying menopausal age Hum. Reprod. Update, September 1, 2005; 11(5): 483 - 493. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. S. Kok, N. C. Onland-Moret, K. M. van Asselt, C. H. van Gils, Y. T. van der Schouw, D. E. Grobbee, and P. H.M. Peeters No association of estrogen receptor {alpha} and cytochrome P450c17{alpha} polymorphisms with age at menopause in a Dutch cohort Hum. Reprod., February 1, 2005; 20(2): 536 - 542. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. L.C. Hagemans, Y. T. van der Schouw, M. J.J. de Kleijn, W. A. van Staveren, V. J.M. Pop, G. L. Leusink, and D. E. Grobbee Indicators for the total duration of premenopausal endogenous estrogen exposure in relation to BMD Hum. Reprod., September 1, 2004; 19(9): 2163 - 2169. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. R. Palmer, L. Rosenberg, L. A. Wise, N. J. Horton, and L. L. Adams-Campbell Onset of Natural Menopause in African American Women Am J Public Health, February 1, 2003; 93(2): 299 - 306. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.L. Luborsky, P. Meyer, M.F. Sowers, E.B. Gold, and N. Santoro Premature menopause in a multi-ethnic population study of the menopause transition Hum. Reprod., January 1, 2003; 18(1): 199 - 206. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L A Wise, N Krieger, S Zierler, and B L Harlow Lifetime socioeconomic position in relation to onset of perimenopause J. Epidemiol. Community Health, November 1, 2002; 56(11): 851 - 860. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. S. Dorman, A. R. Steenkiste, T. P. Foley, E. S. Strotmeyer, J. P. Burke, L. H. Kuller, and C. K. Kwoh Menopause in Type 1 Diabetic Women: Is it Premature? Diabetes, August 1, 2001; 50(8): 1857 - 1862. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. B. Gold, J. Bromberger, S. Crawford, S. Samuels, G. A. Greendale, S. D. Harlow, and J. Skurnick Factors Associated with Age at Natural Menopause in a Multiethnic Sample of Midlife Women Am. J. Epidemiol., May 1, 2001; 153(9): 865 - 874. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Hardy, D. Kuh, and M. Wadsworth Smoking, body mass index, socioeconomic status and the menopausal transition in a British national cohort Int. J. Epidemiol., October 1, 2000; 29(5): 845 - 851. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Richards, D. Kuh, R. Hardy, and M. Wadsworth Lifetime cognitive function and timing of the natural menopause Neurology, July 1, 1999; 53(2): 308 - 308. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
