HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Submit a response Purchase Article View Shopping Cart Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Linn, S Articles by Rifkind, B M Search for Related Content PubMed PubMed Citation Articles by Linn, S Articles by Rifkind, B M

Serum total cholesterol: HDL cholesterol ratios in US white and black adults by selected demographic and socioeconomic variables (HANES II).

S Linn, R Fulwood, M Carroll, J G Brook, C Johnson, W D Kalsbeek and B M Rifkind

Lipid Metabolism-Atherogenesis Branch, National Heart, Lung and Blood Institute, NIH, Bethesda, MD 20892.

BACKGROUND: Framingham Study findings suggest that total cholesterol (TC):High density lipoprotein cholesterol (HDL-C) ratio is a useful summary of the joint contribution of TC and HDL-C to coronary heart disease (CHD) risk. Information on the distribution of TC:HDL-C in the US population is limited to selected populations and the relationship of the ratio distribution and its correlates has received little attention. METHOD: TC/HDL-C ratios were examined in a representative sample of the United States adult population ages 20 to 74 years, between February 1976 and February 1980 during NHANES II, using stratification and multivariate regression analyses. RESULTS: Age-adjusted mean ratios were higher in men compared with women and were higher in Whites compared with Blacks. White men had the highest TC/HDL-C mean ratios. These relationships remained after stratification by age, education, body mass index, alcohol use, cigarette smoking, and physical activity. Using multivariate analyses, the ratios were positively related to BMI, age, and smoking; and negatively related to female sex, alcohol use, being Black, and physical activity. CONCLUSIONS: Using a ratio reference point of greater than or equal to 4.5 from the Framingham study, at least an estimated 44 million persons ages 25 to 74 years in the US were found to be at higher risk of developing coronary heart disease.

This article has been cited by other articles:

				N. Wattanasuwan, I. A. Khan, R. M. Gowda, B. C. Vasavada, and T. J. Sacchi Effect of Acute Myocardial Infarction on Cholesterol Ratios Chest, October 1, 2001; 120(4): 1196 - 1199. [Abstract] [Full Text] [PDF]

				C. Punyadeera, M-T. van der Merwe, N. J. Crowther, M. Toman, G. P. Schlaphoff, and I. P. Gray Ethnic differences in lipid metabolism in two groups of obese South African women J. Lipid Res., May 1, 2001; 42(5): 760 - 767. [Abstract] [Full Text]