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American Journal of Public Health, Vol. 80, Issue 4 476-477, Copyright © 1990 by American Public Health Association

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Rabies Vaccine Adsorbed: neutralizing antibody titers after three-dose pre-exposure vaccination.

B S Berlin

Bureau of Laboratory and Epidemiological Services, Michigan Department of Public Health, Lansing 48909.

Field trials at several schools of veterinary medicine showed that three-dose pre-exposure rabies vaccination with Rabies Vaccine Adsorbed developed by the Michigan Department of Health elicited neutralization antibody in practically all recipients two to three weeks after immunization. Titers declined during the first six months after vaccination. However, by 18 to 24 months, 98 percent of recipients still had titers equal or greater than a 1:5 dilution of serum.




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B. S. Berlin, Z. F. Udwadia, D. B. Fishbein, L. E. Robinson, and C. R. Rupprecht
Rabies
N. Engl. J. Med., April 14, 1994; 330(15): 1088 - 1089.
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