HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Submit a response Purchase Article View Shopping Cart Alert me when this article is cited Alert me when eLetters are posted Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Kakar, F Articles by Strite, S A Search for Related Content PubMed PubMed Citation Articles by Kakar, F Articles by Strite, S A

Non-contraceptive estrogen use and the risk of gallstone disease in women.

F Kakar, N S Weiss and S A Strite

Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle 98195.

We interviewed 102 women, ages 41-74 years who underwent gallstone surgery between January 1979 and September 1980, and 98 controls selected from the membership files of a large prepaid health care plan in Western Washington, about their past use of certain medications, reproductive history, and physical and demographic characteristics. The risk of gallstone disease among women who used estrogens for at least one year prior to diagnosis of their condition, relative to that of other women, was 1.18 (95% CI: 0.65-2.13). Standardization for the effects of age, race, obesity, parity, thiazide use, and history of high blood pressure did not alter appreciably the estimate of relative risk. Among estrogen users, the duration of use was similar in cases and controls. Our findings suggest that if non-contraceptive estrogen use is a risk factor for gallstone disease (requiring surgery) in women, its effect is very small.

This article has been cited by other articles:

				D. J. Cirillo, R. B. Wallace, R. J. Rodabough, P. Greenland, A. Z. LaCroix, M. C. Limacher, and J. C. Larson Effect of Estrogen Therapy on Gallbladder Disease JAMA, January 19, 2005; 293(3): 330 - 339. [Abstract] [Full Text] [PDF]

				Cholecystitis, Biliary Tract Surgery, and Pancreatitis Obstet. Gynecol., October 1, 2004; 104(4_suppl): 17S - 24S. [Full Text] [PDF]

				H. D. Nelson, L. L. Humphrey, P. Nygren, S. M. Teutsch, and J. D. Allan Postmenopausal Hormone Replacement Therapy: Scientific Review JAMA, August 21, 2002; 288(7): 872 - 881. [Abstract] [Full Text] [PDF]

				J. A. Simon, D. B. Hunninghake, S. K. Agarwal, F. Lin, J. A. Cauley, C. C. Ireland, J. H. Pickar, and for the Heart and Estrogen/progestin Replacement S Effect of Estrogen plus Progestin on Risk for Biliary Tract Surgery in Postmenopausal Women with Coronary Artery Disease: The Heart and Estrogen/progestin Replacement Study Ann Intern Med, October 2, 2001; 135(7): 493 - 501. [Abstract] [Full Text] [PDF]