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The persistence of Shigella flexneri in the United States: increasing role of adult males.

R V Tauxe, R C McDonald, N Hargrett-Bean and P A Blake

Division of Bacterial Diseases, Center for Infectious Diseases, Atlanta, GA 30333.

The annual reported isolation rate of Shigella flexneri decreased from 1964 to 1973, but has remained constant since then at 1 per 100,000. Between 1975 and 1985, the median age of males from whom S. flexneri was isolated rose from 5 to 26 years. During this time, the isolation rate of S. flexneri rose more than five-fold among men, did not change in adult women, and decreased in children. By 1985, 23 per cent of reported S. flexneri isolates came from men aged 20-49. Increased male homosexual transmission of S. flexneri is a possible explanation for these findings.

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