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About two-thirds of 90 clinics treating phenylketonuria (PKU) now recommend indefinite continuation of a low phenylalanine diet as compared to 1978 when fewer than one-fourth had this policy. The percentage of children maintained on diet has increased markedly for six to eight year-olds. Greater conservatism in clinic diet recommendations likely reflects reports of adverse consequences following diet discontinuation and negative individual clinic experiences.
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L. A. Gleason, K. Michals, R. Matalon, P. Langenberg, and S. Kamath A Treatment Program for Adolescents With Phenylketonuria Clinical Pediatrics, June 1, 1992; 31(6): 331 - 335. [Abstract] [PDF] |
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